Forskolin-a Natural Root Extract of Coleus Forskohlii- a Mini Review
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Strategies to Improve the Production of Forskolin from Hairy Root Cultures of Coleus forskohlii Briq
The aim of this study was to elucidate the effect of elicitors and precursors on the production of forskolin from the hairy root cultures of Coleus forskohlii Briq. Hairy root cultures were established from leaf explants by infecting with Agrobacterium rhizogenes strain A4 on MS basal medium. Suspension cultures of hairy root cultures were initiated in MS medium containing IBA (1.0 mg/L), casei...
متن کاملQuantitative analysis of forskolin in Coleus forskohlii (Lamiaceae) by reversed-phase liquid chromatography.
A rapid method was developed for the evaluation of forskolin in Coleus forskohlii Briq. (Lamiaceae). Forskolin was quantitated in the root and stem of dried C. forskohlii and in 17 market products by reversed-phase liquid chromatography (LC) with a photodiode array detector at 210 nm. The temperature was held constant at 30 degrees C, and the retention time of forskolin was approximately 6.8 mi...
متن کاملTotal biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
Forskolin is a unique structurally complex labdane-type diterpenoid used in the treatment of glaucoma and heart failure based on its activity as a cyclic AMP booster. Commercial production of forskolin relies exclusively on extraction from its only known natural source, the plant Coleus forskohlii, in which forskolin accumulates in the root cork. Here, we report the discovery of five cytochrome...
متن کامل“In Vitro Anticancer Activity of an Ethanol Extract of Coleus forskohlii Root against Liver Cancer cell line”
Human liver cancer is the fifth most common cancer in the world. It is one of the serious health problems in most developing countries. The present investigation proved that ethanol extract of Coleus forskohlii root extract significantly suppressed the growth and induced the apoptosis in the liver cancer (HepG2) cell lines. IC50 dose was measured with Methyl thiazolyl tetrazolium (MTT) assay. 6...
متن کاملColeus spp.: Micropropagation and In Vitro Production of Secondary Metabolites
Coleus spp. have long been prized for their colorful foliage, which may combine shades of green, yellow, pink, red and maroon. They are plants for all locations. Besides their ornamental nature, Coleus spp. are also valued in folk medicine. C. blumei Benth., a natural hybrid of several Coleus spp. is an ornamental plant growing all over the world in an enormous number of different cultivars tha...
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تاریخ انتشار 2014